Khalid Iqbal Selected Research

Microtubule-Associated Proteins (Microtubule-Associated Protein 2)

1/2021	Thiamme2-G, a Novel O-GlcNAcase Inhibitor, Reduces Tau Hyperphosphorylation and Rescues Cognitive Impairment in Mice.
1/2020	Elevation of casein kinase 1ε associated with TDP-43 and tau pathologies in Alzheimer's disease.
9/2019	Pathological Alterations of Tau in Alzheimer's Disease and 3xTg-AD Mouse Brains.
1/2018	Recent developments with tau-based drug discovery.
1/2017	Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis.
3/2014	Microtubule-associated protein tau as a therapeutic target in Alzheimer's disease.
1/2014	Tau pathology involves protein phosphatase 2A in parkinsonism-dementia of Guam.
1/2013	Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) enhances tau expression.
1/2012	Differential effects of an O-GlcNAcase inhibitor on tau phosphorylation.
3/2011	Splicing factor SC35 promotes tau expression through stabilization of its mRNA.

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Khalid Iqbal Research Topics

Disease

114	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 02/2001
26	Tauopathies 01/2021 - 08/2002
18	Cognitive Dysfunction 01/2021 - 01/2009
10	Dementia (Dementias) 01/2022 - 01/2005
9	Down Syndrome (Down's Syndrome) 01/2017 - 04/2008
8	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 03/2002
7	Memory Disorders (Memory Loss) 01/2017 - 08/2010
6	Neuroinflammatory Diseases 01/2021 - 12/2009
5	Neoplasms (Cancer) 06/2019 - 01/2012
4	Brain Ischemia (Cerebral Ischemia) 05/2022 - 06/2013
4	Body Weight (Weight, Body) 01/2021 - 01/2014
4	Amyloid Plaque 01/2019 - 11/2005
3	Stroke (Strokes) 05/2022 - 01/2011
3	Typhoid Fever (Typhoid) 01/2022 - 11/2020
3	Insulin Resistance 10/2018 - 04/2015
3	Acidosis 01/2018 - 01/2013
3	Frontotemporal Dementia (Semantic Dementia) 01/2005 - 08/2002
2	Ischemia 05/2022 - 01/2018
2	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 05/2022 - 09/2015
2	Vitamin D Deficiency 08/2021 - 07/2009
2	Learning Disabilities (Learning Disability) 08/2020 - 01/2019
2	Hypoglycemia (Reactive Hypoglycemia) 01/2020 - 01/2020
2	Hyperglycemia 01/2020 - 06/2013
2	Chronic Disease (Chronic Diseases) 06/2019 - 01/2018
2	Treatment-Resistant Schizophrenia 07/2018 - 01/2017
2	Neuroblastoma 06/2008 - 08/2003
1	Hyperhomocysteinemia 04/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 04/2022
1	COVID-19 01/2022
1	Infections 01/2022
1	Anemia 08/2021

Drug/Important Bio-Agent (IBA)

34	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2001
23	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2021 - 02/2002
16	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 01/2015 - 09/2003
12	Insulin (Novolin)FDA Link 08/2020 - 11/2009
12	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 07/2004
11	Pharmaceutical PreparationsIBA 01/2022 - 05/2004
11	tau Proteins (tau Protein)IBA 01/2018 - 08/2003
10	Phosphotransferases (Kinase)IBA 05/2022 - 02/2001
10	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2005
8	Amyloid beta-PeptidesIBA 01/2017 - 01/2005
7	Peptides (Polypeptides)IBA 01/2021 - 01/2010
6	Biomarkers (Surrogate Marker)IBA 06/2019 - 12/2009
6	EnzymesIBA 12/2018 - 04/2002
6	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2018 - 01/2004
6	CalpainIBA 01/2018 - 11/2005
6	Nerve Growth Factors (Neurotrophins)IBA 06/2017 - 01/2010
5	Protein Kinases (Protein Kinase)IBA 01/2018 - 12/2002
4	Glycogen Synthase (Synthase I)IBA 05/2022 - 01/2004
4	asparaginylendopeptidase (legumain)IBA 01/2018 - 01/2013
4	Ciliary Neurotrophic Factor (CNTF)IBA 02/2015 - 01/2010
4	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 12/2014 - 04/2003
4	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 04/2011 - 01/2004
3	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2021 - 01/2013
3	Sevoflurane (Ultane)FDA LinkGeneric 08/2020 - 01/2017
3	Propofol (Diprivan)FDA LinkGeneric 01/2020 - 01/2014
3	Protein Isoforms (Isoforms)IBA 01/2017 - 10/2006
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2015 - 05/2004
3	Amino Acids FDA Link 09/2011 - 06/2009
2	AntibodiesIBA 05/2022 - 01/2018
2	MicronutrientsIBA 04/2022 - 08/2021
2	PrionsIBA 01/2022 - 01/2021
2	Casein Kinases (Casein Kinase)IBA 01/2020 - 10/2017
2	Therapeutic UsesIBA 01/2020 - 01/2015
2	Antipsychotic Agents (Antipsychotics)IBA 07/2018 - 01/2017
2	Amisulpride (Solian)IBA 07/2018 - 01/2017
2	Clozapine (Clozaril)FDA LinkGeneric 07/2018 - 01/2017
2	DNA-Binding Proteins (DNA Binding Protein)IBA 06/2017 - 01/2017
2	UbiquitinIBA 01/2017 - 11/2005
2	Dyrk KinasesIBA 06/2015 - 01/2013
2	Memantine (Namenda)FDA Link 01/2015 - 05/2004
2	Flavin-Adenine Dinucleotide (FAD)IBA 04/2013 - 01/2012
2	CalcineurinIBA 01/2011 - 11/2005
2	Tyrosine (L-Tyrosine)FDA Link 01/2011 - 09/2008
2	Secretory Phospholipases A2IBA 07/2010 - 12/2009
2	Neurofilament ProteinsIBA 06/2008 - 03/2002
2	CalciumIBA 12/2007 - 11/2005
2	Protein Subunits (Protein Subunit)IBA 01/2007 - 08/2002
2	tissue-factor-pathway inhibitor 2 (PP5)IBA 01/2005 - 01/2004
2	Glycogen Synthase Kinase 3IBA 11/2004 - 04/2003
2	Mitogen-Activated Protein KinasesIBA 09/2003 - 12/2002
1	triphenyltetrazoliumIBA 05/2022
1	HomocysteineIBA 04/2022
1	tedizolidIBA 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2022
1	Typhoid-Paratyphoid Vaccines (Typhoid Vaccines)FDA Link 01/2022
1	Oxazolidinones (2 Oxazolidone)IBA 01/2022
1	Linezolid (Zyvox)FDA Link 01/2022
1	Folic Acid (Vitamin M)FDA LinkGeneric 08/2021
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 08/2021
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2021
1	hexosaminidase CIBA 01/2021
1	Conjugate VaccinesIBA 11/2020
1	Isoflurane FDA LinkGeneric 01/2020

Therapy/Procedure

7	Anesthesia 08/2020 - 01/2009
6	General Anesthesia 08/2020 - 01/2014
5	Therapeutics 05/2022 - 06/2010
3	Intranasal Administration 08/2020 - 02/2016
2	Injections 01/2020 - 07/2009
2	Mediterranean Diet 01/2018 - 03/2017